[Murph]

I would try turning off;
ATM Original
Tougher Bridges
Tougher Trains
These are all redundant, and are already featured in other mods you have enabled.
Also the 4GB Client thing might cause instability problems if you do not have enough RAM in your video card. Try one of the ones with a little less RAM usage.
Make sure that whatever version of the TrackIr mod you use is enabled LAST- after all the other mods. Otherwise it may not work properly.