[{HVY-E}Jinxx]

To put it simply, yes.

Think of JSGME like a shopping bag. They're all the same. The difference is what you put in the bag.
JSGME is merely the tool you use to select which mods to activate. You can use the same JSGME for both HSFX and UP. What you can't do is use all the same mods. Some mods are made only for UP and some for HSFX, then others will work with both.

Hope I didn't confuse you too much.

S!