[{HVY-E}Jinxx]

No one has really ever used the in-game voice chat due to it's resource/bandwidth issues. Most everyone I know of uses either Ventrillo (also very resource hungry but sounds great) or Teamspeak (Not quite as clear as Vent, but uses just a fraction of the resources/bandwidth of Vent).

Bottom line, if you have the PC and Bandwidth to use it, Ventrillo is a good choice, but if you're plagued by an ISP that doesn't give you a whole lot of bandwidth, especially upstream, use TS.